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Simparica TRIO for Dogs 88.1-132 lbs (Red)

280 customer reviews

Simparica TRIO for Dogs 88.1-132 lbs (Red)

$151.87 $108.48

  • $151.87 $108.48
  • $275.77 $196.98
  • $524.27 $374.48
  • Simparica Trio Brown is suitable for dogs weighing between 88.1-132.0lbs
  • Offers broad-spectrum protection
  • Provides flexible dosing options (72mg sarolaner, 1.44mg moxidectin, & 300mg pyrantel)
  • Aids in the treatment of both external and internal parasites
  • Protects against five different species of ticks
  • Available in 3, 6 and 12 doses pack sizes
  • Information
  • Features
  • How to Use
  • Safety
  • Simparica TRIO Ingredients
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Simparica Trio Brown for 88.1-132 lbs Dogs

Simparica Trio Brown for dogs is a highly palatable, multi-spectrum treatment that protects against both external and internal parasites. This flavoured, monthly chewable formula is recommended for use in 8 weeks and older puppies and dogs that weigh 2.8 lbs or more.

Simparica Trio (88.1–132.0 lbs) prevents heartworm infection, treats and controls roundworms, and hookworm infections. It kills adult fleas, and treats and prevents flea infections. This monthly formula treats and controls lone star ticks, Gulf coast ticks, American dog ticks, black-legged ticks, and brown dog ticks. Simparica Trio belongs to the isoxazoline class and it is highly recommended to use this treatment with caution on dogs with seizures or other neurologic disorders. The safe use of Simparica Trio in breeding, pregnant or lactating dogs has not been evaluated.

Simparica Trio (sarolaner, moxidectin, and pyrantel) All-in-one Treatment for Dogs

Simparica Trio brown pack is a blend of three premium ingredients (sarolaner: 72mg, moxidectin: 1.44mg, and pyrantel: 300mg) precisely designed for 88.1-132.0 lbs dogs. The trio formula (sarolaner, moxidectin, and pyrantel) starts working immediately after administration. Sarolaner works at neuromuscular junctions in parasites causing uncontrolled activity and death in the end. Moxidectin interfers with chloride channel mediated neurotransmission in parasites and cause death. Pyrantel works as a neuromuscular blocking agent resulting in paralysis of the insect causing death. A single dose of Simparica Trio kills fleas, ticks, prevents heartworms, kills deer ticks, and prevents Lyme disease, and treats and controls roundworm and hookworm infections.


  • Three-in-one treatment for dogs
  • Palatable liver-flavored chews
  • Protects dogs from fleas and ticks
  • Aids in monthly heartworm prevention
  • Effective against as many as 5 tick species

How to Use

  • Pick the appropriate pack based on the weight of your dog.
  • One oral chew should be directly administered into the dog’s mouth.
  • It can also be mixed with the pet’s meal.
  • Repeat dosage once every month for better results.
  • For further assistance, kindly refer to product pack.


  • Suitable for puppies and dogs over 8 weeks of age.
  • Keep chews out of the reach of children.
  • Wash hands thoroughly after administering.
  • Store oral treatment in a dry and cool place.
  • Treatment is only meant for dogs.


Warnings and Precautions

  • Use with caution for dogs that have a history of seizure attacks, tremors, ataxia, etc.
  • The safe use of this treatment on pregnant, lactating, and breeding dogs has not yet be evaluated.

Simparica TRIO Ingredients

Sarolaner, Moxidectin, and Pyrantel

Simparica TRIO Reviews (280)

Product Rated 4.7/5 (280 customer reviews)
Eric Farlinger – April 07, 2024


Anna Howington – April 07, 2024
Ordering Simparica

Ordering was easy and product received timely.

Tsuifong Wu – April 06, 2024
The one flea. Tick and heart worm medici

We adopted our two dogs and our vet suggested this medication when we adopted and this is the one we have been using since we adopted it. It works well..

Lisa Harris – March 31, 2024
Flea Meds

Best price that I was able to find on the web..

Eugene – March 28, 2024
Easy peasy

Thank you for helping me save a bundle here..

Marlene Coley – March 26, 2024
Simparica Trio

Excellent price and fairly quick shipping. This my second order with them and am pleased..

Ulissa Bryan – March 26, 2024

I can give my baby less pills which she is not a fan of..

David Peterson – March 23, 2024
Great all in one product!

We’ve been using Simparica Trio on our boys for a couple years. It’s nice to have a once a month product that takes care of ticks and heartworm. We’ve found this works better than front line as far as controlling ticks. I definitely recommend giving it a try!.

DeAnne Wareham – March 20, 2024

I have never had a problem with any orders from BudgetVetCare. They have the same products but much less expensive! I highly recommend!.

luis salazar – March 20, 2024
Best price

Simparica Trio is the best all-around protection available. It arrived by mail with no issues. Will buy again..