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Simparica TRIO for Dogs 2.8-5.5 lbs (Yellow)

594 customer reviews


Simparica TRIO for Dogs 2.8-5.5 lbs (Yellow)

$34.19 $47.87

  • $47.87 $34.19
  • $93.14 $66.53

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Simparica TRIO for Dogs 5.6-11 lbs (Purple)

Simparica TRIO for Dogs 5.6-11 lbs (Purple)

$49.24 $35.17
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Simparica TRIO for Dogs 11.1-22 lbs (Caramel)

Simparica TRIO for Dogs 11.1-22 lbs (Caramel)

$51.98 $37.13
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Simparica TRIO for Dogs 22.1-44 lbs (Blue)

Simparica TRIO for Dogs 22.1-44 lbs (Blue)

$61.59 $43.99
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Simparica TRIO for Dogs 44.1-88 lbs (Green)

Simparica TRIO for Dogs 44.1-88 lbs (Green)

$80.79 $57.71
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Simparica TRIO for Dogs above 88 lbs (Brown)

Simparica TRIO for Dogs above 88 lbs (Brown)

$98.63 $70.45
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highlights
  • Simparica Trio Gold is suitable for dogs weighing between 2.8-5.5lbs
  • Offers broad-spectrum protection
  • Provides flexible dosing options (3mg sarolaner, 0.06mg moxidectin, & 12.5mg pyrantel)
  • Aids in the treatment of both external and internal parasites
  • Protects against five different species of ticks
  • Available in 3, 6 and 12 doses pack sizes
Information
tab article

Simparica TRIO Chewable Tablets for Dogs 2.8–5.5 lbs (Yellow)

Simparica TRIO Yellow Pack is specially formulated for very small dogs and puppies weighing 2.8–5.5 lbs, providing comprehensive monthly parasite protection in a single, easy-to-administer chew. Each tablet contains 3 mg sarolaner, 0.06 mg moxidectin, and 12.5 mg pyrantel, delivering multi-layered protection against internal and external parasites.

This liver-flavored chew helps prevent heartworm disease, treats and controls roundworms and hookworms, and kills fleas and ticks, including multiple tick species. The yellow color-coded pack ensures accurate dosing for smaller dogs, making it simple to choose the right strength.

Ideal for very small breeds, this pack offers a convenient, all-in-one solution to support monthly parasite protection and overall wellbeing.

Why It Stands Out

  • All-in-one monthly protection against multiple parasites
  • Helps prevent heartworm disease
  • Starts killing fleas within approximately 4 hours
  • Protects against 6 species of ticks
  • Treats and controls roundworms and hookworms
  • Helps prevent flea tapeworm infections by direct killing fleas
  • Highly palatable liver flavor for easy dosing
  • FDA-approved combination preventive

What It Covers

Simparica TRIO helps protect your dog against:

  • Heartworms – prevents heartworm disease with monthly use
  • Fleas – kills fleas and helps stop infestations
  • Ticks – controls six species including:
  • Gulf Coast tick
  • American dog tick
  • Lone star tick
  • Black-legged (deer) tick
  • Brown dog tick
  • Asian longhorned tick
  • Intestinal worms – treats and controls roundworms and hookworms

Helps reduce the risk of tapeworm infections associated with flea exposure by direct killing adult fleas.

How the Formula Works

Simparica TRIO combines sarolaner, moxidectin, and pyrantel to deliver comprehensive protection. Sarolaner targets fleas and ticks, moxidectin helps prevent heartworm disease, and pyrantel treats and controls intestinal worms.

This combination works systemically to provide multi-layered protection, help eliminate parasites and maintain consistent coverage with monthly use.

How to Use
  • Ensure your dog is tested for heartworm infection before starting
  • Administer one chew orally once a month
  • Give on the same date each month for consistent protection
  • Can be given with or without food
  • Ensure your dog consumes the full dose
  • If a dose is missed, give it as soon as possible and resume monthly dosing

Dosage Guide:

Dog Weight (lbs) Pack Color Sarolaner (mg) Moxidectin (mg) Pyrantel (mg) Tablets
2.8 – 5.5 Yellow 3 mg 0.06 mg 12.5 mg One
5.6 – 11 Purple 6 mg 0.12 mg 25 mg One
11.1 – 22 Caramel 12 mg 0.24 mg 50 mg One
22.1 – 44 Blue 24 mg 0.48 mg 100 mg One
44.1 – 88 Green 48 mg 0.96 mg 200 mg One
88.1 – 132 Brown 72 mg 1.44 mg 300 mg One
Administer an appropriate combination of tablets
Safety
  • For use in dogs only
  • Suitable for dogs and puppies 8 weeks of age and older weighing at least 2.8 lbs
  • Dogs should be tested for heartworm infection prior to use
  • Use as directed by your veterinarian
  • Keep out of reach of children and other pets

Precautions

  • The safe use has not been evaluated in breeding, pregnant, or lactating dogs
  • Use with caution in dogs with a history of seizures or neurological disorders
  • Consult your veterinarian if your dog has existing health concerns or is on other medications
  • Treat all pets in the household to help prevent flea reinfestation

Storage & Disposal

  • Store at or below 30°C (86°F)
  • Keep in a cool, dry place
  • Keep away from children and pets
  • Dispose of packaging responsibly after use
Simparica TRIO Ingredients

Sarolaner, Moxidectin, and Pyrantel

FAQ

Q. What is Simparica TRIO for Dogs used for?

A. Simparica TRIO is a monthly all-in-one chew that helps prevent heartworm disease, treats and controls roundworms and hookworms, and kills fleas and ticks.

Q. How often should I give Simparica TRIO?

A. It should be given once every month on the same date to maintain consistent protection against parasites.

Q. Do I need a heartworm test before starting Simparica TRIO?

A. Yes. Dogs should be tested for heartworm infection before starting treatment, as recommended by veterinarians.

Q. How quickly does Simparica TRIO start working?

A. It begins killing fleas within approximately 4 hours and reaches full effectiveness within 8 hours, helping stop infestations quickly.

Q. What parasites does Simparica TRIO protect against?

A. It protects against heartworms, fleas, ticks (6 species), roundworms, and hookworms, and also helps reduce the risk of flea tapeworm infections by killing fleas that can carry tapeworms.

Q. Can Simparica TRIO be given with food?

A. Yes. The chew can be given with or without food, depending on your dog’s preference.

Q. Is Simparica TRIO suitable for puppies?

A. Yes. It is suitable for dogs and puppies 8 weeks of age and older weighing at least 2.8 lbs.

Q. What should I do if I miss a dose?

A. If you miss a dose, give it as soon as possible and resume the regular monthly schedule to maintain protection.

Q. Does Simparica TRIO replace multiple parasite treatments?

A. Yes. It combines heartworm prevention, flea and tick control, and intestinal worm treatment into one monthly chew, simplifying your dog’s care routine.

Q. Are there any precautions when using Simparica TRIO?

A. Use with caution in dogs with a history of seizures and consult your veterinarian if your dog has underlying health conditions or is on other medications.

Q. Where can I buy Simparica TRIO for Dogs online?

A. Simparica TRIO is available through BudgetVetCare, making it easy to order genuine parasite protection products from the comfort of your home.

Q. How can BudgetVetCare help me save on pet treatments?

A. BudgetVetCare offers competitive pricing, seasonal deals, and multi-pack options, helping you manage your pet’s healthcare routine without stretching your budget.

Please Note: The information provided here is compiled from manufacturer data and publicly available product resources for general understanding. It is not intended to replace professional veterinary guidance. As every pet’s needs may vary, always consult your veterinarian before starting or changing any treatment.

Simparica TRIO Reviews (594)

Product Rated 4.8/5 (594 customer reviews)

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Estefany Abarca – September 22, 2026
Without Prescription

I bought this med because I was trying to save some money by not having to go to the vet. I loved it. .

Darlene Wade – September 21, 2026
Simparica Trio

I’m pleased with the product and it take as long as I expected. .

Hugo Merrick – September 20, 2026
Easy Chew Routine

My dog accepts the chew readily, making treatment time much easier..

Bonnie Marker – September 19, 2026
Great service and reasonable price

Ordering the product from this website was easy reasonable price and it came on time. I’m very pleased with it and will order from.

Estelle Morgan – September 17, 2026
Easy Chew Care

My dog takes it easily..

Everett Sloan – September 10, 2026
Easy Chew

My dog takes it easily..

Giselle Tarn – September 03, 2026
Easy Chew Option

My dog takes it without hesitation..

Beyron Lusk – August 24, 2026
Simple Flea Routine

Convenient chew that is easy to include in regular care..

Brysen Hale – August 17, 2026
Simple All-in-One Care

One chew makes our regular parasite routine much easier..

Zyren Knox – August 10, 2026
All in One Care

One chew makes parasite prevention simple..