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Comfortis Plus (Trifexis) Chewable Tablets for Xlarge Dogs 27-54 kg (60 to 120lbs) Brown

182 customer reviews

Comfortis Plus (Trifexis) Chewable Tablets for Xlarge Dogs 27-54 kg (60 to 120lbs) Brown

$128.81 $92.01

  • $128.81 $92.01
  • $249.55 $178.25

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Comfortis Plus (Trifexis) Chewable Tablets for Xlarge Dogs 27-54 kg (60 to 120lbs) Brown
Bravecto For Extra Large Dogs 40-56kg (88 to 123lbs) Pink
Total: $197.63 $187.75
  • (View Product)
  • Comfortis Plus Brown Pack - Specifically designed for extra large dogs
  • Suitable and safe for dogs weighing between 60-120 lbs
  • Offers appropriate dosing (1620 mg spinosad and 27 mg milbemycin oxime)
  • Beef-flavored tasty chewable tablet for easy and convenient administration
  • Treats and control fleas and intestinal worms (hookworms, roundworms, whipworms)
  • Prevent heartworm disease and control flea allergy dermatitis
  • Available in highly palatable 6 and 12 chews pack sizes
  • Information
  • Features
  • How to Use
  • Safety
  • Comfortis Plus (Trifexis) Ingredients
tab article

Comfortis Plus Brown Pack for X-Large Dogs 60-120 lbs

Comfortis Plus for extra large dogs is a #1 vet-recommended flea and worming treatment for extra large-sized dogs. It is a beef-flavored chewable tablet that efficiently kills fleas and protects against intestinal worms and heartworms. It is a fast-acting flea control treatment as it starts killing fleas within just 30 minutes of administration. This way, it prevents flea infestations and controls flea allergy dermatitis. This reliable treatment also treats and controls intestinal worms like hookworms, roundworms, and whipworms, and prevents the deadly heartworm disease.

Comfortis Plus Brown is recommended for extra large dogs from eight weeks of age and weighing between 60 and 120lbs (27 and 54 kg).

Comfortis Plus (Spinosad+Milbemycin Oxime) Flea, Worm & Heartworm Treatment

Comfortis Plus is formulated using two powerful treatments: Spinosad and Milbemycin Oxime. Spinosad works on fleas, whereas Milbemycin Oxime works on internal parasites like intestinal worms and heartworms.

Spinosad acts on the nervous system of the fleas, triggering their nerve cells. This leads to involuntary muscle contractions and tremors, which leads to the destruction of fleas. It starts killing fleas within 30 minutes and eliminates 100% of them within 24 hours.

The other active ingredient, Milbemycin Oxime, attacks intestinal worms and immature forms of heartworms. The anthelmintic effectively controls heartworms and intestinal worms protecting the dog from harmful infections.


  • Advanced version of comfortis with added features
  • New age formula for effectively treating fleas and worms
  • Prevents and controls heartworm infection
  • Starts working on fleas within 30 minutes of administration
  • Treats and prevents worms including hookworm, roundworm, and whipworm
  • Helps in the prevention of flea infestation
  • Supports in the control program of flea allergy dermatitis

How to Use

  • Dosage depends on dog weight.
  • Administer it directly into the mouth or mix it with food.
  • Ensure the dog finishes the whole food for complete dosage.


  • Do not use in cats.
  • Keep out of reach of children and other pets.
  • Store it in a cool and dry place.
  • Avoid using on puppies less than 8 weeks of age.
  • Safety in pregnant and lactating dogs has not been evaluated yet.


  • No known side effects found yet.

Comfortis Plus (Trifexis) Ingredients

  • Spinosad
  • Milbemycin Oxime

Comfortis Plus (Trifexis) Reviews (182)

Product Rated 4.6/5 (182 customer reviews)
Nick – May 07, 2024
Nice wormer

It removes multiple types of worms with ease..

Zander – April 30, 2024
Worthy Product

It works exactly what it labels says!.

Benicio – April 23, 2024
Great product

Provides the necessary care and protection against parasites without causing any trouble or discomfort to my pets..

Greyson – April 15, 2024
Affordable Quality

I found it here at a fraction of the cost compared to other retailers..

Abel – April 07, 2024
Perfectly Sized Tablets

Designed for easy administration, these tablets offer convenience and peace of mind..

Kelley Gray – March 25, 2024

As a dog rescue I appreciate you guys so much your products are a great price your customer service is awesome I tell everybody about you.

August – March 25, 2024

Found the best price, the lowest on the market!.

Aryan – March 23, 2024
Value for money

The website offers low prices and reliable delivery.

Stanley – March 15, 2024

Great prices for all the brand-name products. Lowest prices I have ever seen for such products..

Nicola Devine – March 09, 2024
Free of flees

We love it!!.