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Flea and Tick
20% Off
Comfortis Plus
Flea Heartworm Worm
Comfortis Plus (Trifexis) Chewable Tablets For Small Dogs (4.6-9kg) Orange

Comfortis Plus (Trifexis) Chewable Tablets For Small Dogs (4.6-9kg) Orange

92 customer reviews

$105.69 $75.49

  • $105.69 $75.49
  • $207.17 $147.98

Buy Other Packs

Comfortis Plus (Trifexis) Chewable Tablets For XSmall Dogs (2.3-4.5kg) Pink

$101.37 $72.41

Comfortis Plus (Trifexis) Chewable Tablets For Medium Dogs (9.1-18kg) Green

$115.14 $82.24

Comfortis Plus (Trifexis) Chewable Tablets For Large Dogs (18.1-27kg) Blue

$123.12 $87.94

Comfortis Plus (Trifexis) Chewable Tablets For XLarge Dogs (27.1-54kg) Brown

$128.60 $91.86

Product Review

  • All-in-one treatment for fleas, worms, and heartworms in dogs
  • Easy-to-dose highly-palatable tablet
  • Once-a-month administration
  • Kills 100% fleas within 24 hours and prevents further infestations
  • Treats flea allergy dermatitis
  • Treats intestinal worms like hookworms, roundworms, and whipworms
  • Prevents deadly heartworm disease

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What is Comfortis Plus?

 Comfortis plus is an advanced formulation for treating and preventing fleas, worms, and heartworms in dogs. The flavored tablet kills fleas and removes 100% fleas within 24 hours. The monthly dosage controls heartworms and protects dogs against heartworm disease. The oral tablet is also effective in treating intestinal worms including hookworms, roundworms, and whipworms. It prevents intestinal worm infection as well as flea allergy dermatitis.

It is recommended for use in dogs and puppies, from eight weeks of age, and 2.3 kg body weight or greater.

How Dose Comfortis Plus for Dogs Work?

Comfortis Plus contains Spinosad and Milbemycin Oxime- two active insecticides. Spinosad is an effective insecticide with no negative effects on the environment. The ingredient acts on the nervous system of the fleas triggering the nerve cells. This leads to into involuntary muscle contractions and tremors leading to the destruction of the fleas. It starts killing fleas within 30 minutes and eliminates 100% fleas within 24 hours.

The other active ingredient – milbemycin oxime attacks intestinal worms and immature forms of heartworms. It eliminates the internal parasites without any side effects to your dog. The anthelmintic effectively controls heartworms and intestinal worms protecting the dog from harmful infection. The oral chew controls both internal and external parasites.  

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  • Advanced version of comfortis with added features
  • New age formula for effectively treating fleas and worms
  • Prevents and controls heartworm infection
  • Starts working on fleas within 30 minutes of administration
  • Treats and prevents worms including hookworm, roundworm, and whipworm
  • Helps in the prevention of flea infestation
  • Supports in the control program of flea allergy dermatitis

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  • Dosage depends on dog weight.
  • Administer it directly into the mouth or mix it with food.
  • Ensure the dog finishes the whole food for complete dosage.

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  • Do not use in cats.
  • Keep out of reach of children and other pets.
  • Store it in a cool and dry place.
  • Avoid using on puppies less than 8 weeks of age.
  • Safety in pregnant and lactating dogs has not been evaluated yet.


  • No known side effects found yet.

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  • Spinosad
  • Milbemycin Oxime

Comfortis Plus (Trifexis) Reviews (92)

Product Rated 4.7/5 (92 customer reviews)
Frances – June 10, 2022

Saves me at least $15 a treatment than what my vet used to charge.

Christi Compton – May 16, 2022
Very excited to try this product.

I've been using Comfortis for flea and tick control for about 12 years. Since the first time i tried it, it's been my go to and it's always my #1 recommendation. I'm very excited to see the heart and intestinal worm component has been added. One pill, once a month and Done!.

Greig – April 04, 2022
Very Happy

I am writing because I'm very pleased with this product..

Walker – March 15, 2022
Worth to buy this

This is an effective product that works as a great preventive against fleas and ticks and heartworm as well..

Kelly – March 07, 2022
Does the job

Comfortis Plus does more than the fleas..