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Nexgard Combo for Cat

(25 customer reviews)
You Pay
3 Pack
6 Pack
12 Pack
You Pay
3 Pack
6 Pack
12 Pack
  • Broad spectrum spot on treatment
  • Kills roundworms and tapeworms
  • Suitable for cats above 8 weeks of age
  • One month protection from heartworms
  • Kills fleas within 24 hours and ticks within 48 hours
  • Information
  • Features
  • How to Use
  • Safety
  • Nexgard Combo Ingredients
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What is Nexgard Combo for Cats?

Nexgard combo is a multi spectrum spot-on treatment for cats. It protects your feline from a wide range of parasites. The topical treatment for cats kills the external parasites like fleas and ticks and cures the infection caused due to internal worms. Along with killing fleas, it also prevents re-infestation of fleas and ticks for four weeks and five weeks, respectively.

The treatment is composed of a triad of active substances consisting of esfoxolaner, eprinomectin, and praziquantel. It kills fleas within 24 hours of administration. It terminates flea before they lay eggs preventing household contamination. Within 48 hours of administration, existing ticks are killed. It is also efficient is treating roundworms, hookworms, tapeworms, ear mites and preventing deadly heartworm infestations.

How does Nexgard Combo for Cats Work?

Nexgard combo is made with three active ingredients that function in different ways to kill external and internal parasites. Esafoxolaner acts as an ectoparasiticide, having efficacy in killing external parasites that live on feline skin. After application of the treatment, the substance invades the nerve cells of parasites through neurotransmission- (neuron signals); this disrupts the nervous system of fleas and ticks resulting into their termination.

Esafoxolaner acts on flea nerve cells before it lays eggs so household contamination is prevented. Active ingredient Praziquantel and Eprinomectin work against internal worms. Praziquantel attacks on the cell membrane of tapeworms resulting in its termination. Similarly, Eprinomectin will paralyze roundworms by disrupting its nerve and muscle cells and prevents heartworms.


  • One month protection from the danger of heartworm disease.
  • Protects against external & internal parasites
  • High efficacy in killing ear mites
  • Cure infection of internal worms such as tapeworm, feline lungworm and vesicle worm
  • Kills ticks (Ixodes ricinus)
  • Treats infection of feline lungworms
  • Used as part FAD treatment strategy –control of flea allergy dermatitis.
  • Safe to use on kittens for eight weeks of age and 0.8 kg weight.

How to Use

  • Cut open the blister and remove the applicator
  • Hold it in upright position, pulling the plunger slightly.
  • Twist and pull of the cap
  • Decide the spot between the area of skull and shoulder blade of cat.
  • Part the fur until the skin is visible, place the tip of the applicator, and empty the entire content on that spot
  • Make sure to apply the treatment on the skin and not on the fur.


  • Apply it on the skin of the cat; a spot that they cannot lick it off; optimal area will be between the head and neck.
  • Dispose the treatment immediately after use
  • Wash your hands immediately after application
  • Avoid sleeping with your cat for 24 hours of application
  • Do not repeat the application before one month
  • Do not administer orally
  • Should specifically be given to cats and not to any other animal.
  • Restrict children and people from touching the area of application until it is fully dried


  • It has not proven efficacy on pregnant and lactating cats


  • Do not provide the treatment to cat in case of hypersensitivity.
  • Avoid the treatment if cat is allergic to any of the active ingredients

Nexgard Combo Ingredients

Esafoxolaner, Eprinomectin and Praziquantel.

Nexgard Combo Reviews (25)

Product Rated 4.8/5 (25 customer reviews)
Joanna – May 09, 2024
Nice worming option

It is helpful in removing various types of worms from my baby..

Sue Ann Kimbler – May 03, 2024

I’ve heard amazing things about this product and can’t wait to try it!.

Barbara – May 03, 2024
Great product

Nexgard Combo is the only product that DOESN'T send my cat hiding under the bed after application. She almost yawns after I apply it. I think that is because unlike other products I've tried, this one doesn't burn. That's a very big deal..

Wendy Shepard – April 24, 2024
Great experience

We will be back! Phenomenal pricing and prompt service.

Michael Palmer – April 19, 2024
Super fast delivery

Super fast delivery, best price around. Will definitely continue using this vendor..

theresa perrault – April 14, 2024
great product

I have 2 cats who are indoor/outdoor,and have not seen any fleas. This is also is good on one of my cats who is allergic to other products..

Bryan – April 08, 2024
Effortless Protection

Thanks for making pet care so easy and affordable..

Karen Boldroff – March 31, 2024
Flea medication for cats

It came on schedule, as promised. I applied to cat. So far, so good, I believe it's working fine! The price was very reasonable. I will buy from them again!.

M. C. Imhauser – March 26, 2024

Thank you for the competitive price and for sending it so quickly!.

Castiel – March 10, 2024
Powerful Solution

Works very well for keeping all those external as well as internal parasites at bay!.