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Nexgard Combo for Cats

(96 customer reviews)
Nexgard Combo For Cats Upto 5.5lbs

Nexgard Combo For Cats Upto 5.5lbs
Pack
Qty
You Pay
3 Pack
$46.93
6 Pack
$92.01
12 Pack
$181.19
Nexgard Combo For Cats 5.5lbs - 16.5lbs

Nexgard Combo For Cats 5.5lbs - 16.5lbs
Pack
Qty
You Pay
3 Pack
$48.89
6 Pack
$94.95
12 Pack
$186.09
highlights
  • Broad spectrum spot on treatment
  • Kills roundworms and tapeworms
  • Suitable for cats above 8 weeks of age
  • One month protection from heartworms
  • Kills fleas within 24 hours and ticks within 48 hours
Information
tab article

What is Nexgard Combo for Cats?

Nexgard combo is a multi spectrum spot-on treatment for cats. It protects your feline from a wide range of parasites. The topical treatment for cats kills the external parasites like fleas and ticks and cures the infection caused due to internal worms. Along with killing fleas, it also prevents re-infestation of fleas and ticks for four weeks and five weeks, respectively.

The treatment is composed of a triad of active substances consisting of esfoxolaner, eprinomectin, and praziquantel. It kills fleas within 24 hours of administration. It terminates flea before they lay eggs preventing household contamination. Within 48 hours of administration, existing ticks are killed. It is also efficient is treating roundworms, hookworms, tapeworms, ear mites and preventing deadly heartworm infestations.

How does Nexgard Combo for Cats Work?

Nexgard combo is made with three active ingredients that function in different ways to kill external and internal parasites. Esafoxolaner acts as an ectoparasiticide, having efficacy in killing external parasites that live on feline skin. After application of the treatment, the substance invades the nerve cells of parasites through neurotransmission- (neuron signals); this disrupts the nervous system of fleas and ticks resulting into their termination.

Esafoxolaner acts on flea nerve cells before it lays eggs so household contamination is prevented. Active ingredient Praziquantel and Eprinomectin work against internal worms. Praziquantel attacks on the cell membrane of tapeworms resulting in its termination. Similarly, Eprinomectin will paralyze roundworms by disrupting its nerve and muscle cells and prevents heartworms.

Features
  • One month protection from the danger of heartworm disease.
  • Protects against external & internal parasites
  • High efficacy in killing ear mites
  • Cure infection of internal worms such as tapeworm, feline lungworm and vesicle worm
  • Kills ticks (Ixodes ricinus)
  • Treats infection of feline lungworms
  • Used as part FAD treatment strategy –control of flea allergy dermatitis.
  • Safe to use on kittens for eight weeks of age and 0.8 kg weight.
How to Use
  • Cut open the blister and remove the applicator
  • Hold it in upright position, pulling the plunger slightly.
  • Twist and pull of the cap
  • Decide the spot between the area of skull and shoulder blade of cat.
  • Part the fur until the skin is visible, place the tip of the applicator, and empty the entire content on that spot
  • Make sure to apply the treatment on the skin and not on the fur.
  • For best results, follow the below nexgard combo dosage guide for cats

Dosage

Cat Weight (lbs) Volume (ml) Esafoxolaner (mg) Eprinomectin (mg) Praziquantel (mg) Pack Color 
Up to 5.5 lbs (2.5 kg) 0.3 3.60 mg 1.20 mg 24.90 mg Purple 
5.6-16.5 lbs (2.5-7.5 kg) 0.9 10.80 mg 3.60 mg 74.70 mg Yellow 
Safety
  • Apply it on the skin of the cat; a spot that they cannot lick it off; optimal area will be between the head and neck.
  • Dispose the treatment immediately after use
  • Wash your hands immediately after application
  • Avoid sleeping with your cat for 24 hours of application
  • Do not repeat the application before one month
  • Do not administer orally
  • Should specifically be given to cats and not to any other animal.
  • Restrict children and people from touching the area of application until it is fully dried

Contradictions

  • It has not proven efficacy on pregnant and lactating cats

Warning

  • Do not provide the treatment to cat in case of hypersensitivity.
  • Avoid the treatment if cat is allergic to any of the active ingredients
Nexgard Combo Ingredients

Esafoxolaner, Eprinomectin and Praziquantel.

Nexgard Combo Reviews (96)

Product Rated 4.8/5 (96 customer reviews)

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Prynn Ash – August 17, 2026
One Treatment Convenience

Makes broader parasite care easier with a single treatment..

Orik Vire – August 10, 2026
One Simple Treatment

Convenient option for broader parasite protection..

Orik Vire – August 03, 2026
All-in-One Coverage

Covers multiple issues in one treatment. Very efficient..

Orlyn Kade – July 27, 2026
Full Coverage Solution

One treatment handles everything. Makes pet care so easy..

Pryce Dorn – July 20, 2026
Dual Action

Combines benefits in one product..

Prynn Vale – July 13, 2026
Dual Action

Combines multiple protections..

Prynn Hale – July 06, 2026
Dual Benefit

Combines protection effectively..

Phaedra Knox – June 29, 2026
Dual Action

Great combination product for pets..

Pax Rowan – June 22, 2026
Dual Benefit

Combines multiple protections well..

Parker Shaw – June 15, 2026
Cat Protection

Covers both fleas and internal parasites..